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New additions to the MSRC Webshop - Over the Garden Fence - Discussion Areas - MSRC Message Boards - Message Board - Yuku

Mon, 09 Nov 2009 07:58:20 -0800

New to the Webshop!

MaximuS Bear is MSRC's mascot and now you can own your very own MaximuS!

To find out more go to MaximuS's page - http://www.securio.net/msrc/index.cfm/fa/shopdetails/Product_ID/68/preview/1

Show your support for MSRC by wearing one of our MaximuS Bear mascot or MSRC lapel badges.

To find out more go to the MSRC Lapel Badges page - http://www.securio.net/msrc/index.cfm/fa/MSRCLapelBadges

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Mon, 09 Nov 2009 05:08:27 -0800

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Mon, 09 Nov 2009 03:47:44 -0800

National Differences

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Mon, 09 Nov 2009 02:08:26 -0800

Multiple Sclerosis Resource Centre Latest MS News

Sun, 08 Nov 2009 23:22:47 -0800

Teenage obesity - possible link to future Multiple Sclerosis?

Being obese as a teenager may be linked with an increased risk of multiple sclerosis as an adult, researchers say.

A 40-year study of 238,000 women found those who were obese at 18 had twice the risk of developing MS compared to women who were slimmer at that age.

Yet body size during childhood or adulthood was not found to be associated with MS risk, the US researchers report in Neurology.

But an MS charity warned more research was needed to confirm the findings.

Researchers from Harvard School of Public Health used data from nurses taking part in a large study on diet, lifestyle factors and health.

Over the course of the study, 593 women were diagnosed with MS, a condition caused by the loss of nerve fibres and their protective myelin sheath in the brain and spinal cord, which causes neurological damage.

The researchers compared the risk of the disease with body mass index (BMI) - a ratio of weight to height - at age 18.

Participants were also asked to describe their body size using a series of diagrams at the age of five, 10 and 20.

The study showed that those with an "obese" BMI of 30 or larger at age 18 had more than twice the risk of developing MS.

There was also a smaller increased risk in those who were classed as overweight .

The results were the same after accounting for smoking status and physical activity level.

Body shape

When comparing the risk of MS with self-reported body shape, the researchers found no association between childhood obesity and the future chances of developing the disease.

They also found no risk associated with adult obesity.

But women who had a larger body size at 20 years of age also had almost twice the risk of MS compared to women who reported a thinner body size.

Previous research has linked high levels of vitamin D with a reduced risk of MS and the researchers point out that obesity is associated with low vitamin D levels in the body.

The researchers suggest fatty tissue produces substances that affect the immune system, which may also provide a link with the chances of developing MS.

Further research should look at confirming the findings in men and individuals from different ethnic groups as well as comparing with vitamin D levels, they said.

"Our results suggest that weight during adolescence, rather than childhood or adulthood, is critical in determining the risk of MS," said study author Kassandra Munger, ScD, of Harvard School of Public Health in Boston.

"There's a lot of research supporting the idea that adolescence may be an important time for development of disease, so what we have found is consistent with that."

She added: "Teaching and practicing obesity prevention from the start - but especially during teenage years - may be an important step in reducing the risk of MS later in life for women."

Susan Kohlhaas, research communications officer for the MS Society, said: "This study does not account for several other factors that may play a role in causing MS. Based on that, more work is needed.

"As such, it is difficult to determine whether teenage obesity could be a possible factor in causing MS in women."

Source: BBC News � British Broadcasting Corporation 2009 (09/11/09)

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Sun, 08 Nov 2009 06:15:24 -0800

We will remember them

Multiple Sclerosis Resource Centre TYSABRI�

Sat, 07 Nov 2009 01:01:52 -0800

Elan updates Tysabri label to warn of risks of brain disease

ELAN HAS updated the label on its breakthrough multiple sclerosis (MS) drug Tysabri to reflect the increased risk of patients contracting a serious brain disease if they are on the drug for more than two years.

The company announced last night that, effective immediately, it was updating the label on the drug in the US market following consultation with the US regulator, the Food and Drug Administration (FDA).

The FDA is expected to confirm the move on its own website in the coming days.

The company and its US partner, Biogen Idec, had come under pressure when the European Medicines Agency (EMEA) announced recently that it was opening a review of the risks and benefits of the drug after 24 people had contracted the rare and potentially fatal brain disease progressive multifocal leukoencephalopathy (PML). Four of those patients had died subsequently, the EMEA said.

The news came as a shock. Just a week earlier, the FDA had stated that, as of September 8th, there were just 13 known cases of the disease in Tysabri patients.

Last night Elan and Biogen updated the patient medication guide and the prescriber information guide on the drug�s website to reflect the new label.

A spokeswoman for the company said there was no other change in the wording of the label. In particular, the guidance of a one-in-1,000 risk of contracting PML is unchanged.

Both companies have indicated that talks with the FDA are ongoing as more information about the drug emerges.

The EMEA review is continuing separately. Elan said last night it expected a similar change of wording would be approved in talks with the European regulator.

Source: The Irish Times � 2009 Irishtimes.com (07/11/09)

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Fri, 06 Nov 2009 13:49:26 -0800

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Fri, 06 Nov 2009 09:05:28 -0800

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Fri, 06 Nov 2009 08:58:43 -0800